Common Fish Diseases and Symptoms: Complete Identification Guide

You notice something odd: your fish is hiding more than usual, its fins look ragged, or strange white spots appear overnight. What is it? Is it Ich, fin rot, velvet, or something else entirely? The next 24-48 hours are critical.

Fish diseases progress 5-10× faster than diseases in mammals due to their aquatic environment and cold-blooded metabolism. A bacterial infection that would take 7 days to become serious in a dog can kill a fish in 36 hours. Misdiagnosis = wrong treatment = fish death + wasted money.

Chapter 2: Symptom-Based Quick Diagnosis

Use this table to match your fish’s symptoms to possible diseases. Check multiple symptoms for accurate identification.

Symptom Observed Possible Diseases Urgency Level
White salt-grain spots Ich, Epistylis, Lymphocystis 🔴 HIGH (treat within 24h)
Gold/rust dust coating Velvet (Oodinium) 🔴 CRITICAL (treat immediately)
Frayed/shredded fins Fin Rot, Columnaris 🟡 MEDIUM (treat within 48h)
Cottony white patches Fungal Infection, Columnaris 🟡 MEDIUM (treat within 48h)
Swollen/bloated body Dropsy, Constipation, Tumors 🔴 HIGH (often fatal if dropsy)
Pinecone scales (raised) Dropsy 🔴 CRITICAL (90% fatal)
Floating/sinking, loss of balance Swim Bladder Disease, Constipation 🟡 MEDIUM (often reversible)
Bulging eye(s) Popeye, Bacterial Infection 🟡 MEDIUM (treat within 72h)
Holes in head/lateral line Hole-in-the-Head, Hexamita 🟡 MEDIUM (nutritional + parasitic)
Thread-like worms hanging off body Anchor Worms 🟡 MEDIUM (painful but treatable)
Rapid gill movement, gasping Gill Flukes, Ammonia Poisoning, Low O2 🔴 HIGH (check water params first)
Clamped fins Stress, ANY disease, Poor Water Quality 🟢 LOW (early warning sign)
Red streaks/bloody patches Bacterial Septicemia, Hemorrhagic Disease 🔴 CRITICAL (treat immediately)
Scratching/flashing on objects Ich, Velvet, Flukes, Gill Parasites 🔴 HIGH (parasites present)
⚠️ Critical Rule: If you see 2+ severe symptoms (pinecone scales, red streaks, gold dust, rapid breathing), this is a medical emergency. Start treatment within 2 hours and consider euthanasia if fish is suffering with no hope of recovery.

Chapter 3: Ich (White Spot Disease)

🔬 Ich (Ichthyophthirius multifiliis)

Visual Symptoms:

  • Salt-grain white spots on body, fins, gills
  • Scratching/flashing against rocks/decorations
  • Rapid gill movement (if gills infected)
  • Lethargy + loss of appetite

Cause:

Protozoan parasite Ichthyophthirius multifiliis. Introduced via new fish, plants, or contaminated equipment.

Prevalence:

Most common fish disease — affects 60-70% of aquariums at some point.

Contagiousness:

⚠️ Highly contagious. Spreads to all fish in tank within 3-7 days.

Treatment:

  • Medication: Ich-X, Malachite Green, API Super Ick Cure
  • Dosage: 5ml Ich-X per 10 gallons, daily for 7-10 days
  • Temperature: Raise to 86°F (speeds up life cycle)
  • Duration: 7-10 days minimum (continue 3 days after spots gone)
  • Cost: $12-$25 for 60-gallon treatment

Success Rate:

92-96% cure rate with medication + heat. Only 78-85% with heat alone.

Prevention:

  • Quarantine all new fish for 4 weeks
  • Avoid temperature drops >3°F in 24 hours
  • Maintain low stress (good water quality, no overcrowding)

📖 For detailed Ich treatment protocol, see Article 38: How to Treat Ich in Aquarium

Chapter 4: Fin Rot

🩹 Fin Rot (Bacterial/Fungal)

Visual Symptoms:

  • Frayed fin edges (looks like torn paper)
  • White/black discoloration on fin margins
  • Progressive fin loss (disappears over days)
  • Red streaks at fin base (advanced)

Severity Levels:

Stage Appearance Cure Rate
Mild Outer 10-20% of fins affected, minor fraying 98% (heals in 7-10 days)
Moderate 50% fin loss, white edges, fish still active 85-92% (heals in 14-21 days)
Severe Fins down to body, red inflammation, lethargy 60-75% (may not fully regrow)

Cause:

Bacterial infection (Pseudomonas, Aeromonas) or fungal infection following fin damage. Triggered by poor water quality, fin nipping, rough handling.

Treatment:

  • Medication: API Fin and Body Cure, Seachem KanaPlex, Maracyn
  • Dosage: Follow package instructions (varies by product)
  • Water Changes: 25% every 2 days during treatment
  • Duration: 7-14 days
  • Cost: $8-$18 for 40-gallon treatment

Success Rate:

85-98% depending on severity and water quality improvement.

Prevention:

  • Keep ammonia and nitrite at 0 ppm
  • Separate aggressive fish (fin nippers)
  • Remove sharp decorations
  • Feed high-quality, vitamin-rich foods

📖 For complete fin rot treatment guide, see Article 36: Fin Rot Treatment for Beginners

Chapter 5: Velvet (Oodinium)

✨ Velvet (Oodinium pillularis)

Visual Symptoms:

  • Gold/rust dust coating on skin (looks like velvet fabric)
  • Spots too small to count (vs. Ich’s countable spots)
  • Scratching (more intense than Ich)
  • Clamped fins + rapid gill movement
  • Peeling skin (advanced stage)

How to Confirm:

Shine a flashlight at an angle on fish — velvet reflects gold/copper shimmer. Ich spots are white and raised.

Danger Level:

🔴 MORE DEADLY than Ich. Velvet reproduces 3-5× faster. Can kill fish in 3-5 days if gills are heavily infected.

Treatment:

  • Medication: Copper sulfate (CuSO4), Cupramine, or Ich-X (contains copper)
  • Dosage: Maintain 0.15-0.20 ppm copper (test daily with copper kit)
  • Darkness: Cover tank with towels for 3 days (velvet needs light to photosynthesize)
  • Temperature: Raise to 82-84°F
  • Duration: 10-14 days
  • Cost: $15-$30 for copper + test kit

Success Rate:

80-92% if caught early (within 48 hours). Only 40-60% if gills are severely damaged.

Prevention:

  • Quarantine new fish 4 weeks (velvet has long incubation)
  • Avoid sudden temperature changes
  • UV sterilizer kills free-swimming velvet (50-70% reduction)
🚨 Velvet Emergency Protocol:
If you see gold dust + rapid breathing + peeling skin, this is a medical emergency. Start treatment within 2 hours. Consider moving fish to hospital tank with copper to avoid killing invertebrates.

Chapter 6: Dropsy

💧 Dropsy (Fluid Accumulation)

Visual Symptoms:

  • Pinecone scales (scales raised outward due to fluid buildup)
  • Swollen/bloated belly
  • Bulging eyes (often)
  • Pale gills
  • Lethargy + sitting at bottom

Pinecone Test:

View fish from above. If scales stick out like a pinecone, it’s dropsy. If scales are flat, it’s constipation or bloating.

Cause:

NOT a disease itself — it’s a symptom of organ failure (usually kidney/liver) caused by bacteria (Aeromonas), poor water quality, or internal parasites.

Prognosis:

🔴 90-95% fatal. Once scales pinecone, organ damage is usually irreversible. Early intervention (before pineconing) has 30-40% success rate.

Treatment (Often Unsuccessful):

  • Antibiotics: Maracyn Two, API General Cure (metronidazole)
  • Epsom Salt: 1 tsp per 5 gallons (helps reduce swelling)
  • Hospital Tank: Move to separate tank to monitor closely
  • Duration: 7-14 days (if fish responds)
  • Cost: $15-$40

Success Rate:

5-10% once scales pinecone. 30-40% if caught at early bloating stage before scales raise.

When to Euthanize:

  • No improvement after 7 days of treatment
  • Fish can’t swim or stay upright
  • Refuses food for 5+ days
  • Visible suffering (gasping, struggling)

Prevention:

  • Maintain pristine water quality (0 ammonia, 0 nitrite, <20 ppm nitrate)
  • Feed varied, high-quality diet
  • Quarantine new fish
  • Avoid overfeeding (causes internal bacterial growth)
💔 Humane Euthanasia: If dropsy is advanced (pinecone scales + no eating for 7 days + no response to treatment), consider humane euthanasia with clove oil to end suffering. Dropsy recovery is extremely rare once pineconing occurs.

Chapter 7: Swim Bladder Disease

🎈 Swim Bladder Disease

Visual Symptoms:

  • Floating at surface (can’t swim down)
  • Sinking to bottom (can’t swim up)
  • Swimming upside-down or sideways
  • Struggles to maintain position
  • Otherwise normal appetite/behavior

Cause:

Swim bladder malfunction due to:

  • Constipation (70% of cases) — compressed swim bladder
  • Overfeeding — bloated stomach presses on bladder
  • Bacterial infection — inflammation of swim bladder
  • Birth defect (fancy goldfish, balloon mollies) — genetic

Treatment (varies by cause):

For Constipation-Caused (Most Common):

  • Fasting: Don’t feed for 2-3 days
  • Pea Treatment: Feed blanched, peeled pea on Day 3 (acts as laxative)
  • Epsom Salt: 1 tbsp per 5 gallons (softens stool)
  • Duration: 3-7 days
  • Cost: $3 (Epsom salt only)

For Bacterial Infection:

  • Antibiotics: API General Cure, Maracyn
  • Duration: 7-10 days
  • Cost: $12-$18

Success Rate:

75-85% if constipation-related. Only 30-50% if bacterial or genetic.

Prevention:

  • Soak dry flakes/pellets before feeding (prevents gas)
  • Feed small portions 2× daily instead of 1 large meal
  • Offer peas once weekly as fiber
  • Avoid overfeeding (most common cause)

Chapter 8: Fungal Infections

🍄 Fungal Infections (Saprolegnia)

Visual Symptoms:

  • Cotton-like white/gray tufts on body, fins, eyes
  • Fuzzy appearance (like moldy bread)
  • Usually on wounds or damaged areas
  • May spread to healthy tissue if untreated

Fungus vs. Columnaris (Look-Alike):

Characteristic Fungus Columnaris
Appearance Thick, 3D cotton tufts Flat, thin white film
Growth Speed Slow (days-weeks) Fast (hours-days)
Location Usually on wounds Mouth, fins, body (anywhere)
Treatment Antifungal (malachite green) Antibiotic (Maracyn)

Cause:

Fungus (Saprolegnia) grows on dead tissue, wounds, or weakened fish. Always a secondary infection following injury, stress, or other disease.

Treatment:

  • Medication: API Fungus Cure, Malachite Green, Methylene Blue
  • Salt Bath: 1 tbsp per gallon for 10-15 minutes (mild cases)
  • Duration: 7-10 days
  • Cost: $8-$15

Success Rate:

90-95% if caught early. Lower if underlying cause (injury, stress) isn’t addressed.

Prevention:

  • Remove sharp decorations (prevent injuries)
  • Maintain good water quality (fungus thrives in dirty water)
  • Quarantine injured fish for observation
  • Treat wounds immediately with antifungal

Chapter 9: Columnaris (Cotton Wool Disease)

⚡ Columnaris (Flexibacter columnaris)

Visual Symptoms:

  • White/gray patches on mouth, fins, gills
  • “Saddleback” lesion across dorsal area
  • Frayed fins (looks like fin rot)
  • Rapid progression (grows in hours, not days)
  • Lethargy + loss of appetite

Nickname:

“Mouth Fungus” or “Cotton Wool Disease” (though it’s bacterial, NOT fungal)

Danger Level:

🔴 Fast-acting killer. Can kill fish in 24-48 hours if gills or mouth are infected. Requires immediate treatment.

Treatment:

  • Antibiotics: Maracyn, API Fin and Body Cure, Kanamycin
  • Salt: 1 tbsp per gallon (slows bacterial growth)
  • Temperature: LOWER to 75-76°F (Columnaris thrives in warm water 75-85°F)
  • Duration: 10-14 days
  • Cost: $15-$25

Success Rate:

70-85% if caught in first 24-48 hours. 30-50% if mouth/gills severely affected.

Prevention:

  • Avoid high temps in summer (75-78°F max for vulnerable species)
  • Don’t overcrowd (spreads rapidly in tight spaces)
  • Quarantine new fish (common import disease)

Chapter 10: Hole-in-the-Head Disease

🕳️ Hole-in-the-Head (HITH / Hexamita)

Visual Symptoms:

  • Small holes/pits on head and lateral line
  • White, stringy feces
  • Weight loss despite normal eating
  • Color fading
  • Lesions may enlarge over weeks

Commonly Affects:

Cichlids (especially Oscars, Discus, Angelfish), Gouramis

Cause:

Multifactorial:

  • Hexamita parasite (intestinal flagellate)
  • Nutritional deficiency (vitamin C, D, calcium)
  • Poor water quality (high nitrate >40 ppm)
  • Activated carbon use (removes trace minerals)

Treatment:

  • Medication: Metronidazole (API General Cure), Praziquantel
  • Nutrition: Feed vitamin-enriched foods (spirulina, bloodworms)
  • Water Quality: Lower nitrate to <20 ppm via water changes
  • Duration: 14-21 days (long treatment)
  • Cost: $12-$20

Success Rate:

60-80% if caught early (small pits). 30-50% if large craters formed (indicates severe tissue loss).

Prevention:

  • Feed high-quality cichlid pellets with vitamins
  • Keep nitrate <20 ppm (weekly 30% water changes)
  • Avoid prolonged activated carbon use (2 weeks max)
  • Supplement with fresh vegetables (zucchini, peas)

Chapter 11: Popeye

👁️ Popeye (Exophthalmia)

Visual Symptoms:

  • One or both eyes bulging
  • Cloudy eye(s)
  • Swelling behind eye
  • Eye may rupture in severe cases

Unilateral vs. Bilateral:

Type Cause Treatment
Unilateral (one eye) Physical injury, localized bacterial infection Antibiotics + salt (70-85% success)
Bilateral (both eyes) Systemic infection, organ failure, poor water quality Antibiotics + water quality improvement (50-65% success)

Treatment:

  • Antibiotics: Maracyn, API E.M. Erythromycin
  • Epsom Salt: 1 tsp per 5 gallons (reduces swelling)
  • Water Quality: Large water changes (50% immediately, then 25% daily)
  • Duration: 7-14 days
  • Cost: $10-$18

Success Rate:

70-85% for unilateral. 50-65% for bilateral (indicates more serious underlying issue).

Eye Recovery:

If eye ruptures, fish can survive but will be permanently blind in that eye. Fish adapt well to monocular vision.

Prevention:

  • Maintain 0 ammonia, 0 nitrite (main water quality triggers)
  • Remove sharp objects (prevent eye injuries)
  • Treat any injuries immediately

Chapter 12: Anchor Worms

🪱 Anchor Worms (Lernaea)

Visual Symptoms:

  • Thread-like worms sticking out of fish body (2-10mm long)
  • Red, inflamed entry points
  • Scratching
  • Secondary infections at wound sites

What They Are:

NOT worms — they’re crustacean parasites (Lernaea). Females burrow into fish flesh with anchor-shaped heads.

Treatment:

  • Manual Removal: Use tweezers to pull out visible adults (disinfect wound with iodine after)
  • Medication: Dimilin, Dylox, Potassium Permanganate
  • Repeat Treatment: Every 7 days for 3-4 weeks (kills newly hatched larvae)
  • Cost: $15-$30

Success Rate:

85-95% with full treatment cycle. Reinfection common if treatment stopped early.

Prevention:

  • Quarantine new fish and plants 4 weeks
  • Avoid wild-caught fish/plants
  • Don’t share nets between tanks

Chapter 13: Flukes (Gill & Skin)

🦠 Flukes (Gyrodactylus & Dactylogyrus)

Visual Symptoms:

  • Scratching/flashing (primary sign)
  • Rapid gill movement
  • Excess mucus production (cloudy slime)
  • Clamped fins
  • Lethargy

Types:

  • Skin Flukes (Gyrodactylus): Live birth, spread rapidly
  • Gill Flukes (Dactylogyrus): Lay eggs, cause breathing issues

Diagnosis:

⚠️ Invisible to naked eye. Diagnose by symptoms (scratching + no visible spots) + microscope examination of skin scrape/gill sample.

Treatment:

  • Medication: Praziquantel, API General Cure, Prazi-Pro
  • Salt Bath: 3 tbsp per gallon for 5-10 minutes (kills some flukes)
  • Repeat Treatment: Day 1, 7, 14 (kills adults, then newly hatched larvae)
  • Cost: $12-$25

Success Rate:

80-90% with full 3-dose treatment. Only 40-60% if treatment stopped after 1 dose.

Prevention:

  • Quarantine all new fish 4 weeks
  • Avoid overstocking (flukes spread via contact)
  • Maintain excellent water quality (stress increases susceptibility)

Chapter 14: Bacterial Infections (General)

🦠 Bacterial Infections (Aeromonas, Pseudomonas)

Visual Symptoms (varies by type):

  • Red streaks/patches (septicemia)
  • Open sores/ulcers
  • Cloudy eyes
  • Frayed fins
  • Bloating
  • Lethargy

Common Bacterial Diseases:

Disease Symptoms Severity
Septicemia Red streaks, hemorrhages 🔴 CRITICAL
Ulcer Disease Open sores, exposed muscle 🔴 HIGH
Mouth Rot White patches on lips/mouth 🟡 MEDIUM
Internal Infection Bloating, no appetite, stringy feces 🔴 HIGH

Treatment:

  • Broad-Spectrum Antibiotics: Maracyn Two, API Triple Sulfa, Kanamycin
  • Hospital Tank: Isolate infected fish
  • Water Quality: 50% water change immediately, then 25% daily
  • Duration: 7-14 days
  • Cost: $15-$30

Success Rate:

60-85% depending on severity and antibiotic resistance.

Prevention:

  • Maintain 0 ammonia, 0 nitrite (bacteria thrive in poor water)
  • Quarantine new fish
  • Treat injuries immediately
  • Avoid overstocking (stress weakens immune system)

Chapter 15: Prevention Strategies

5-Layer Disease Prevention System

Layer 1: Quarantine (90% of diseases prevented)

  • Set up 10-20 gallon quarantine tank ($50-$100 total)
  • Quarantine ALL new fish/plants for 4 weeks
  • Observe for symptoms daily
  • Treat preemptively with broad-spectrum medication

Layer 2: Water Quality (70% of diseases prevented)

  • Test weekly: ammonia 0 ppm, nitrite 0 ppm, nitrate <20 ppm
  • Weekly 25-30% water changes
  • Temperature stability (avoid >3°F swings in 24h)
  • Proper filtration (10× turnover rate)

Layer 3: Nutrition (50% immunity boost)

  • Feed high-quality foods (not just flakes)
  • Vary diet: pellets, frozen bloodworms, vegetables
  • Supplement with vitamins (Seachem Vitality)
  • Don’t overfeed (causes ammonia spikes + obesity)

Layer 4: Stress Reduction (60% disease prevention)

  • Don’t overstock (1 inch fish per gallon rule)
  • Separate aggressive species
  • Provide hiding places (caves, plants)
  • Dim lighting during acclimation

Layer 5: Early Detection (doubles survival rate)

  • Observe fish daily (5 minutes)
  • Count fish daily (notice missing fish)
  • Check for behavior changes (hiding, lethargy)
  • Treat symptoms within 24-48 hours

Chapter 16: Frequently Asked Questions

Q1: Can fish diseases spread to humans?

A: Rarely. Most fish diseases are species-specific (only affect fish). Exceptions: Fish TB (Mycobacterium marinum) can cause skin infections in humans with cuts/open wounds. Always wash hands after aquarium maintenance.

Q2: Should I treat the whole tank or just the sick fish?

A: Depends on disease. Treat whole tank: Ich, velvet, flukes, columnaris (contagious). Treat individual fish: Dropsy, popeye, injuries (not contagious). When in doubt, treat whole tank.

Q3: How long should I quarantine new fish?

A: Minimum 4 weeks (28 days). This covers the longest incubation periods for Ich (21-28 days) and velvet (up to 35 days). Observe daily for symptoms.

Q4: Can I use multiple medications at once?

A: ⚠️ NO unless specifically instructed. Mixing medications can create toxic compounds or overload fish. Exception: Malachite green + formalin (pre-mixed in Ich-X). Always follow product instructions.

Q5: Why did my fish get sick despite good water quality?

A: Water quality prevents 70% of diseases, but not 100%. Other causes: new fish introduced disease, weakened immune system from stress, genetic predisposition, injury that became infected.

 

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